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These models allow researchers to zero in on and study the target TSH receptor, thyroid follicular cells, and the feedback mechanisms along the HPT axis to gain insight into how dysregulated thyroid hormone signaling contributes to metabolic disturbances associated with hyperthyroidism Kohn et al

Structural basis for delivery of the intact [Fe2S2] cluster by monothiol glutaredoxin

The metastatic tumor is the same type of cancer as the primary tumor